Heart's Vortex: Intracardiac Blood Flow Phenomena

✍ Scribed by Ares Pasipoularides

• Publisher: Pmph Usa
• Year: 2009
• Tongue: English
• Leaves: 954
• Edition: 1
• Category: Library

✦ Synopsis

                    This outstanding resource provides a comprehensive guide to intracardiac blood flow phenomena and cardiac hemodynamics, including the developmental history, theoretical frameworks, computational fluid dynamics, and practical applications for clinical cardiology, cardiac imaging and embryology. It is not a mere compilation of the most up-to-date scientific data and relevant concepts. Rather, it is an integrated educational means to developing pluridisciplinary background, knowledge, and understanding. Such understanding allows an appreciation of the crucial, albeit heretofore generally unappreciated, importance of intracardiac blood flow phenomena in a host of multifaceted functional and morphogenetic cardiac adaptations.     The book includes over 400 figures, which were prepared by the author and form a vital part of the pedagogy. It is organized in three parts.  Part I, Fundamentals of Intracardiac Flows and Their Measurement, provides comprehensive background from many disciplines that are necessary for a deep and broad understanding and appreciation of intracardiac blood flow phenomena. Such indispensable background spans several chapters and covers necessary mathematics, a brief history of the evolution of ideas and methodological approaches that are relevant to cardiac fluid dynamics and imaging, a qualitative introduction to fluid dynamic stability theory, chapters on physics and fluid dynamics of unsteady blood flows and an intuitive introduction to various kinds of relevant vortical fluid motions.  Part II, Visualization of Intracardiac Blood Flows: Methodologies, Frameworks and Insights, is devoted to pluridisciplinary approaches to the visualization of intracardiac blood flows. It encompasses chapters on 3-D real-time and “live 3-D” echocardiography and Doppler echocardiography, CT tomographic scanning modalities, including multidetector spiral/helical dataset acquisitions, MRI and cardiac MRA, including phase contrast velocity mapping (PCVM), etc. An entire chapter is devoted to the understanding of post processing exploration techniques and the display of tomographic data, including “slice-and-dice” 3-D techniques and cine-MRI. Part II also encompasses an intuitive introduction to CFD as it pertains to intracardiac blood flow simulations, followed—in separate chapters—by conceptually rich treatments of the computational fluid dynamics of ejection and of diastolic filling. An entire chapter is devoted to fluid dynamic epigenetic factors in cardiogenesis and pre- and postnatal cardiac remodeling, and another to clinical and basic science perspectives, and their implications for emerging research frontiers.  Part III contains an Appendix presenting technical aspects of the method of predetermined boundary motion, “PBM,” developed at Duke University by the author and his collaborators.     Key Features:    Highly-illustrated content      with informative, insightful figures and graphs  Specialized focus on      cardiac (patho-)physiology      and intracardiac blood flow phenomena in health and disease, including      interactions of intracardiac flow patterns with myocardial      histoarchitectonics and cardiac morphology      Powerful new pathophysiologic concepts using fluid      dynamic reasoning and digital imaging-assisted, patient-specific      computational fluid-dynamics  Practical applications to physiological and clinical      problems  Extensive coverage of imaging and diagnostics:     High-fidelity multisensor       catheterization,   Angiocardiographic,       noninvasive imaging modalities, including:     Conventional and 3-D real-time and “live        3-D” echocardiography and Doppler        echocardiography   CT        tomographic scanning modalities, including multidetector spiral/helical dataset acquisitions   MRI and        cardiac MRA

✦ Table of Contents

Table of Contents......Page 6
Foreword......Page 18
Prologue......Page 21
Acknowledgments......Page 26
Part I
: Fundamentals of Intracardiac Flows and Their Measurement......Page 28
1: Introduction......Page 29
2: Handy Mathematical Instruments of Thought......Page 62
3: Some Notable Pioneers......Page 142
4: Fluid Dynamics of Unsteady Flow......Page 192
5: Micromanometric, Velocimetric, Angio- and Echocardiographic Measurements......Page 261
6: Cardiac Morphology and Flow Patterns: Structural-Functional Correlations......Page 325
7: Cardiac Cycle and Central Pressure, Flow, and Volume Pulses......Page 350
8: Addendum to Chapters 4, 5, & 7: A Gallery of Multisensor Catheter Cardiodynamics......Page 435
9: Vortex Formation in Fluid Flow......Page 469
Part II: Visualization of Intracardiac Blood Flows: Methodologies, Frameworks, and Insights
......Page 508
10: Cardiac Computed Tomography, Magnetic Resonance, and Real-Time 3-D Echocardiography......Page 509
11: Postprocessing Exploration Techniques and Display of Tomographic Data......Page 609
12: Computational Fluid Dynamics, or "CFD"......Page 650
CFD of Ventricular Ejection......Page 707
14: CFD of Ventricular Filling: Heart's Vortex......Page 762
15: Fluid Dynamic Epigenetic Factors in Cardiogenesis and Remodeling......Page 835
16: A Recapitulation with Clinical and Basic Science Perspectives: Directions of Future Research......Page 878
17: Epilogue......Page 916
Part III: Appendix......Page 918
Index
......Page 931