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Heart failure: The pivotal role of histone deacetylases

✍ Scribed by Hewitson, Ruth; Dargan, James; Collis, David; Green, Aneta; Moorjani, Narain; Ohri, Sunil; Townsend, Paul A.


Book ID
122454406
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
474 KB
Volume
45
Category
Article
ISSN
1357-2725

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Accumulating evidence points to a connection between cancer and transcriptional control by histone acetylation and deacetylation. This is particularly true with regard to the acute leukemias, many of which are caused by fusion proteins that have been created by chromosomal translocations. Genetic re