DNA global hypomethylation in squamous c
โ
Ian M. Smith; Wojciech K. Mydlarz; Suhail K. Mithani; Joseph A. Califano
๐
Article
๐
2007
๐
John Wiley and Sons
๐
French
โ 103 KB
## Abstract Epigenetic changes have been implicated in the pathogenesis of solid tumors, including head and neck squamous cell carcinoma (HNSCC). Prior efforts have primarily examined regional promoter hypermethylation as a silencer of tumor suppressor gene expression. To analyze the global state o