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Head and Neck Squamous-Cell Cancer and its Association with Polymorphic Enzymes of Xenobiotic Metabolism and Repair

✍ Scribed by Harth, Volker; Schäfer, Martin; Abel, Josef; Maintz, Laura; Neuhaus, Thomas; Besuden, Mette; Primke, Robert; Wilkesmann, Anja; Thier, Ricarda; Vetter, Hans; Ko, Yon-Dschun; Brüning, Thomas; Bolt, Hermann M.; Ickstadt, Katja

Book ID
120468569
Publisher
Taylor and Francis Group
Year
2008
Tongue
English
Weight
123 KB
Volume
71
Category
Article
ISSN
1087-2620

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We have investigated the association between the polymorphisms of drug-metabolizing enzymes and susceptibility to head-and-neck squamous-cell carcinoma (HNSCC). PCRbased analysis was performed on 145 Japanese patients and 164 healthy Japanese controls to determine genotypes of polymorphisms in CYP1A