Head and neck osteosarcoma at the University of Washington

✍ Scribed by Dolphine Oda; Linda M. Bavisotto; Rodney A. Schmidt; Michael McNutt; James D. Bruckner; Ernest U. Conrad III; Ernest A. Weymuller Jr

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 78 KB
• Volume: 19
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/(sici)1097-0347(199709)19:6<513::aid-hed9>3.0.co;2-1

✦ Synopsis

Background. Head and neck osteosarcoma is a comparatively rare and aggressive malignancy. Our goal was to examine the experience of head and neck osteosarcoma patients seen over a 15-year period at the University of Washington Medical Center and compare this with the published experience of other centers in terms of demographics, histology, treatment, and survival rate.

Methods. We reviewed surgical pathology slides and clinical treatment records of 13 patients who were treated at the University of Washington Medical Center between 1981 and 1996. A total of 17 cases from 13 patients (13 primary tumors and 4 recurrences) were studied.

Results. There was a slight male predominance, with a male: female ratio of 1.6:1, and median age at diagnosis of 40.9 years (range 22 to 75 years), both slightly higher than has been generally reported. Three of 13 patients had recognized risk factors for the development of osteosarcoma: 2 with a history of prior