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Head and neck irradiation in childhood: Increased risk of developing thyroid disease

✍ Scribed by Kumao Sako

Book ID
104594060
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
259 KB
Volume
7
Category
Article
ISSN
8756-0437

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✦ Synopsis

Abstract

A nodule of the thyroid in a patient with a history of prior irradiation to the head and neck area in childhood is more likely to be malignant than a nodule in the general population

Thirty‐two of 144 such patients (22%) who came to surgery were found to have a carcinoma of the thyroid. A relative short‐term (6 mo) trial with suppressive therapy with a thyroactive agent may be helpful in selecting out those nodules that may be malignant

Although considerable controversy continues to exist as to the proper surgical treatment, our current surgical management involves performing a total extracapsular thyroidectomy.

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## Abstract One hundred fifty‐one patients with a history of childhood irradiation to the head, neck, and thorax had neck explorations (142 for β€œcold” thyroid nodules and 9 for hypercalcemia). Fifty‐nine of the patients had thyroid carcinoma, and associated glandular tumors were found in 20 others.