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HDAC Inhibitors as Targeted Treatment of Frontotemporal Lobar Degeneration

โœ Scribed by Rosse, Gerard


Book ID
127076017
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
145 KB
Volume
4
Category
Article
ISSN
1948-5875

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Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that