HCV Infection and Cryoglobulinemia || Th
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Dammacco, Franco
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Article
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2011
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Springer Milan
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Italian
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The first observation of cold-induced precipitation of serum proteins dates back to 1933, when Wintrobe and Buell first described an unusual case of multiple myeloma in a woman whose serum reversibly precipitated at cold temperatures. In 1947 Lerner and Watson showed cold-precipitable proteins to be