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HCV, Iron, and Oxidative Stress: The New Choreography of Hepcidin

โœ Scribed by Debbie Trinder; Oyekoya T. Ayonrinde; John K. Olynyk

Book ID
119760173
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
251 KB
Volume
134
Category
Article
ISSN
0016-5085

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Hepcidin is a peptide hormone that is secreted by the liver and controls body iron homeostasis. Hepcidin overproduction causes anemia of inflammation, whereas its deficiency leads to hemochromatosis. Inflammation and iron are known extracellular stimuli for hepcidin expression. We found that endopla