Serum samples from 103 blood donors or patients with slightly increased serum levels of liver enzymes were tested for antibodies to hepatitis C virus (anti-HCV) using second generation tests and for HCV RNA by the polymerase chain reaction (PCR). PCR was in a nested configuration, using primer pairs
✦ LIBER ✦
HCV genotypes in Swedish blood donors as correlated to epidemiology, liver disease and hepatitis C virus antibody profile
✍ Scribed by S. Shev; G. Norkrans; Annika Lindholm; A. Widell; Siv Månsson; Ulla Foberg; A. Frydén; S. Hermodsson; Gudrun Lindh; O. Weiland
- Publisher
- Springer-Verlag
- Year
- 1995
- Tongue
- English
- Weight
- 1000 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0300-8126
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In patients with chronic hepatitis C, the influence of the genetic heterogeneity of the hepatitis C virus (HCV) on the progression of liver disease and on the responsiveness to interferon therapy is a matter of controversy. In this study we evaluated the genetic complexity of HCV by singlestrand con