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HBsAg inhibits TLR9-mediated activation and IFN-α production in plasmacytoid dendritic cells

✍ Scribed by Yongfen Xu; Yunwen Hu; Bisheng Shi; Xiaonan Zhang; Jiefei Wang; Zhanqing Zhang; Fang Shen; Qin Zhang; Shuhui Sun; Zhenghong Yuan

Book ID
116757330
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
710 KB
Volume
46
Category
Article
ISSN
0161-5890

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## Abstract ## Background Recombinant replication‐deficient adenoviral vectors (recAd) are attractive candidates for DNA vaccination approaches because they are able to activate the innate and adaptive immune systems. Here we explore the ability of recAd to transduce and activate subsets of dendri