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Hb Indianapolis [β112 (G14) Cys→Arg] as the probable cause of moderate hemolytic anemia and renal damage in a Brazilian patient

✍ Scribed by A. Fattori; E.M. Kimura; D.M. Albuquerque; D.M. Oliveira; F.F. Costa; M.F. Sonati


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
231 KB
Volume
82
Category
Article
ISSN
0361-8609

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✦ Synopsis


Abstract

Hemoglobin (Hb) Indianapolis [β112 (G14) Cys→Arg] is a rare and slightly unstable β‐globin variant. All carriers described to date were clinically normal with only mild reticulocytosis. We report here a case of a Brazilian patient in whom hemolytic anemia and acute renal failure were probably caused by the presence of this variant. Am. J. Hematol., 2007. © 2007 Wiley‐Liss, Inc.