Hb E/Hb LeporeHollandia in a family from Bangladesh
β Scribed by Dr. John S. Waye; Barry Eng; Margaret Patterson; David H. K. Chui; Lebe S. Chang; Bessie Cogionis; Annette O. Poon; Nancy F. Olivieri
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 296 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0361-8609
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A patient originating from Iraq was referred to our laboratory upon suspicion of a hemoglobinopathy. Routine hematological tests revealed a microcytic and slightly anemic phenotype with an elevated HbA 2 suggestive of β€-thalassemia. Samples were obtained for several members of the family which upon
β€-thalassemia and sickle cell disease (SCD) are common disorders in Turkey. Compound heterozygosity for these two disorders (β€ S /β€-thalassemia) is encountered frequently. In this report we present hematological and molecular data of two Turkish siblings with β€ S /β€ del -thalassemia caused by a 290