Havellockate, A Novel Seco and Spiro Lactone Diterpenoid from the Indian Ocean Soft Coral Sinularia granosa

✍ Scribed by Ammanamanchi S.R. Anjaneyulu; Mukku J.R.V. Venugopal; Putcha Sarada; Jon Clardy; Emil Lobkovsky

• Book ID: 104258442
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 477 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)10470-1

✦ Synopsis

The isolationofa novelsecoandSpiroIactonediterpermid, haveIlockate (1) fromthe Indianoceansoft cord .%d~ia granthsa aqd its $tIUCtWe elucid@iqn usingatl Spectral data including X-rayanalysis is presented @1997ElsevierScienceLtd.Allrightsreserved. in our continuing interest on the bio-active seeondary metabolizesof the Indim ocean soft coral%' we have examined the species Sznu/aria granosa collected from the Havelloek Mood of the Andamarsand Nicobar group of Islands of the hsdiarrOcean and present herein the isolation and structure elucidation of a novel seco and SpiroIactone diterpenoid,havelloekate(l), by a study of its spectraldata includingX-ray analysis.

Chemical examination of this species was net reportod earlier. The ethyl acetate extraet of the organism on c&rrnn chromatographyover silieagel furnishedI,z C21H%08, colorless needles,m.p. 212.13°fZ, [a]D+ 23.7.