Hautleistenverlauf bei Homo- und Heterozygotie für Morbus Wilson (hepatolentikuläre Degeneration)

✍ Scribed by W. Vormittag; M. Weninger; R. Willvonseder; F. Wewalka

• Publisher: Springer
• Year: 1976
• Tongue: English
• Weight: 367 KB
• Volume: 31
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00296148

✦ Synopsis

Dermatoglyphics of 11 patients with Wilson's disease and 16 of their clinically asymptomatic relatives of first degree were investigated; 11 of the latter ones were heterozygous in agreement with the turn over rates of Cu-67, 12 under the assumption of autosomal recessive inheritance. On the finger tips the Mb. Wilson patients showed 52.7% whorls, their heterozygous relatives about 40%; compared with our controls (males 33.16%, females 28.82%, Aue-Hauser, 1970) that means a strong increase of this pattern type. On the palm the high frequency of hypothenar patterns in homo- and heterozygotes for Wilson's disease and of loops with accessory triradius in the 4th interdigitum of the patients with Wilson's disease was striking.