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Has familial aggregation in Alzheimer's disease been overestimated?

โœ Scribed by Jeremy M. Silverman; Christopher M. Smith; Deborah B. Marin; James Schmeidler; Sandra Birstein; Melinda Lantz; Kenneth L. Davis; Richard C. Mohs

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
83 KB
Volume
15
Category
Article
ISSN
0885-6230

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## Abstract Regional and global cerebral atrophy are inevitable features of Alzheimer's disease (AD). We assessed volumes and atrophy rates of brain structures in patients with familial AD during the period that they developed symptoms. Five patients with presymptomatic AD and 20 controls had two o