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Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes

✍ Scribed by Al-Ejeh, F; Kumar, R; Wiegmans, A; Lakhani, S R; Brown, M P; Khanna, K K

Book ID
109972554
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
890 KB
Volume
29
Category
Article
ISSN
0950-9232

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## Abstract ## Background Growing evidence suggests that tobacco can affect the responsiveness of cancer cells to treatment, particularly those of head and neck cancer. This article describes the effects of nicotine on the signaling of the death pathway, resulting in a decreased cytotoxicity of va