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Harnessing in vivo siRNA delivery for drug discovery and therapeutic development

✍ Scribed by Xie, Frank Y. (author);Woodle, Martin C. (author);Lu, Patrick Y. (author)

Book ID: 114385267
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 294 KB
Volume: 11
Category: Article
ISSN: 1359-6446
DOI: 10.1016/s1359-6446(05)03668-8

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## Abstract In vivo gene silencing using RNAi plays an important role in target validation and is advancing towards the development of RNAi‐based therapeutics. RNAs were thought to have just two broad functions in cells as messenger RNAs (mRNAs) and ribosomal RNAs, but recently the relevance of mic