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Haplotypes of the low-density lipoprotein receptor-related protein 5 (LRP5) gene: Are they a risk factor in osteoarthritis?

✍ Scribed by A.J.P. Smith; J. Gidley; J.R. Sandy; M.J. Perry; C.J. Elson; J.R. Kirwan; T.D. Spector; M. Doherty; J.L. Bidwell; J.P. Mansell


Book ID
113732270
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
116 KB
Volume
13
Category
Article
ISSN
1063-4584

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Seven novel sequence variants in the hum
✍ Minoru Okubo; Asako Horinishi; Dong-Ho Kim; Tokuo T. Yamamoto; Toshio Murase πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 20 KB

We identified seven novel polymorphisms in the human low density lipoprotein receptor related protein 5 (LRP5) gene. Two of them are predicted to replace amino acid in LRP5 protein (c.314A>G: Q89R and c.4037T>C: V1330A), whereas three are silent mutations in the coding region (c.2268T>C: N740N, c.34