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Haplotype Counting by Next-Generation Sequencing for Ultrasensitive Human DNA Detection

✍ Scribed by Debeljak, Marija; Freed, Donald N.; Welch, Jane A.; Haley, Lisa; Beierl, Katie; Iglehart, Brian S.; Pallavajjala, Aparna; Gocke, Christopher D.; Leffell, Mary S.; Lin, Ming-Tseh; Pevsner, Jonathan; Wheelan, Sarah J.; Eshleman, James R.


Book ID
125857978
Publisher
American Society for Investigative Pathology
Year
2014
Tongue
English
Weight
959 KB
Volume
16
Category
Article
ISSN
1525-1578

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Next-generation sequencing (NGS) technologies can be a boon to human mutation detection given their high throughput: consequently, many genes and samples may be simultaneously studied with high coverage for accurate detection of heterozygotes. In circumstances requiring the intensive study of a few