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Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations

✍ Scribed by Laitman, Yael; Feng, Bing-Jian; Zamir, Itay M; Weitzel, Jeffrey N; Duncan, Paul; Port, Danielle; Thirthagiri, Eswary; Teo, Soo-Hwang; Evans, Gareth; Latif, Ayse; Newman, William G; Gershoni-Baruch, Ruth; Zidan, Jamal; Shimon-Paluch, Shani; Goldgar, David; Friedman, Eitan


Book ID
119960437
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
449 KB
Volume
21
Category
Article
ISSN
1018-4813

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The 185delAG mutation (c.68_69delAG) in
✍ Monique Buisson; Olga AnczukΓ³w; Almoutassem B. Zetoune; Mark D. Ware; Sylvie Maz πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 243 KB

The 185delAG mutation (c.68\_69delAG; ter39) in the BRCA1 gene is a founder Jewish Ashkenazi mutation that is carried by 1% of this population and has been identified in thousands of breast or ovarian cancer patients. We have previously described that transcripts bearing this mutation, as well as tr