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Haploinsufficiency of SOX5, a member of the SOX (SRY-related HMG-box) family of transcription factors is a cause of intellectual disability

✍ Scribed by Schanze, Ina; Schanze, Denny; Bacino, Carlos A.; Douzgou, Sofia; Kerr, Bronwyn; Zenker, Martin


Book ID
120515118
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
995 KB
Volume
56
Category
Article
ISSN
1769-7212

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## Abstract Mouse embryonic fibroblasts (MEFs) can be differentiated into fully functional chondrocytes in response to bone morphogenetic protein‐2 (BMP‐2). The expression of Sox9, a critical transcription factor for the multiple steps of chondrogenesis, has been reported to be upregulated during t