Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
โ Scribed by Gilliland, D. Gary; Song, Woo-Joo; Sullivan, Melanie G.; Legare, Robert D.; Hutchings, Sarah; Tan, Xiaolian; Kufrin, Dubravka; Ratajczak, Janina; Resende, Isabel C.; Haworth, Catherine; Hock, Randy; Loh, Mignon; Felix, Carolyn; Roy, Denis-Claude; Busque, Lambert; Kurnit, David; Willman, Cheryl; Gewirtz, Alan M.; Speck, Nancy A.; Bushweller, John H.; Li, Frederick P.; Gardiner, Katheleen; Poncz, Mortimer; Maris, John M.
- Book ID
- 109514985
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 986 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1061-4036
- DOI
- 10.1038/13793
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๐ SIMILAR VOLUMES
## Abstract Familial platelet disorder with propensity to acute myelogenous leukemia, or FPD/AML (OMIM #601399), is a rare autosomal dominant condition, with only 12 families reported. It is characterized by qualitative and quantitative platelet defects and predisposition to the development of myel