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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

โœ Scribed by Gilliland, D. Gary; Song, Woo-Joo; Sullivan, Melanie G.; Legare, Robert D.; Hutchings, Sarah; Tan, Xiaolian; Kufrin, Dubravka; Ratajczak, Janina; Resende, Isabel C.; Haworth, Catherine; Hock, Randy; Loh, Mignon; Felix, Carolyn; Roy, Denis-Claude; Busque, Lambert; Kurnit, David; Willman, Cheryl; Gewirtz, Alan M.; Speck, Nancy A.; Bushweller, John H.; Li, Frederick P.; Gardiner, Katheleen; Poncz, Mortimer; Maris, John M.


Book ID
109514985
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
986 KB
Volume
23
Category
Article
ISSN
1061-4036

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Familial platelet disorder with propensi
โœ Antonella Minelli; Emanuela Maserati; Gabriele Rossi; Maria Ester Bernardo; Pier ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 95 KB

## Abstract Familial platelet disorder with propensity to acute myelogenous leukemia, or FPD/AML (OMIM #601399), is a rare autosomal dominant condition, with only 12 families reported. It is characterized by qualitative and quantitative platelet defects and predisposition to the development of myel