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Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

✍ Scribed by Borg, Joseph; Papadopoulos, Petros; Georgitsi, Marianthi; Gutiérrez, Laura; Grech, Godfrey; Fanis, Pavlos; Phylactides, Marios; Verkerk, Annemieke J M H; van der Spek, Peter J; Scerri, Christian A


Book ID
109914635
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
919 KB
Volume
42
Category
Article
ISSN
1061-4036

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Homozygotes for the hereditary persisten
✍ B. Ringelhann; C. T. A. Acquaye; J. H. Oldham; F. I. D. Konotey-Ahulu; G. Yawson 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 594 KB

Two sons of a previously reported Ghanaian homozygote for the hereditary persistence of fetal hemoglobin (HPFH) (Ringelhann et al., 1970) also are HPFH homozygotes. In addition, another unrelated adult Ghanaian homozygote has been detected. All of these Ghanaian homozygotes as well as three American