Handbook of Toxicologic Pathology

✍ Scribed by Wanda M. Haschek and Colin G. Rousseaux (Eds.)

• Publisher: Academic Press
• Year: 1991
• Tongue: English
• Leaves: 1071
• Category: Library

✦ Synopsis

This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come.

Key Features
Comprehensive, ''user friendly'' reference text on toxicologic pathology
Large, easy-to-use 8 1/2'' x 11'', double-column format
Systematic approach to each organ or system
More than 500 illustrations and 90 tables complement the text
Over 2,000 references for easy access to the primary literature
Unique chapters written by leading authorities

✦ Table of Contents

Content:
Front Matter, Page iii
Copyright, Page iv
Dedication, Page v
Contributors, Pages xix-xxi
Preface, Pages xxiii-xxiv, Wanda M. Haschek, Colin G. Rousseaux
1 - Toxicologic Pathology: An Introduction, Pages 1-8, Robert W. Leader
2 - The Pathologist in Toxicologic Testing and Evaluation, Pages 9-21, David C. Dodd
3 - Evaluation of Altered Morphology, Pages 23-35, Thomas J. Bucci
4 - Quantitative Techniques for Morphological Evaluation, Pages 37-48, Michael J. Evans, Susan G. Shami, John R. Wells
5 - Biochemical Basis of Toxicity, Pages 49-70, Elizabeth H. Jeffery
6 - Biochemical Mechanisms of Toxic Cell Injury, Pages 71-89, Marlene E. Kyle, John L. Farber
7 - Chemical Carcinogenesis, Pages 91-129, Robert R. Maronpot
8 - The Limitations of Toxicologic Pathology, Pages 131-142, Zadok Ruben, Colin G. Rousseaux
9 - Regulatory Aspects and Potential Pitfalls of Toxicologic Pathology, Pages 143-153, Paul K. Hildebrandt
10 - Risk Assessment, Pages 155-163, Gary A. Van Gelder
11 - Skin and Oral Mucosa, Pages 165-193, Andres J.P. Klein-Szanto, Claudio J. Conti, C. Marcelo Aldaz
12 - Gastrointestinal Tract, Pages 195-251, Timothy A. Bertram
13 - Pancreas, Pages 253-278, Daniel S. Longnecker, Glenn L. Wilson
14 - Hepatobiliary System, Pages 279-314, James A. Popp, Russell C. Cattley
15 - Urinary System, Pages 315-387, Carl L. Alden, Charles H. Frith
16 - Blood and Bone Marrow, Pages 389-419, Richard D. Irons
17 - Immune System, Pages 421-487, Henk-Jan Schuurman, Magda A.M. Krajnc-Franken, C. Frieke Kuper, Henk van Loveren, Joseph G. Vos
18 - Skeletal System, Pages 489-537, J. Carroll Woodard, Webster S.S. Jee
19 - Cardiovascular and Skeletal Muscle Systems, Pages 539-624, John F. Van Vleet, Victor J. Ferrans, Eugene Herman
20 - Nervous System, Pages 625-674, Adalbert Koestner, Stata Norton
21 - Endocrine System, Pages 675-760, Charles C. Capen, Ronald A. DeLellis, John T. Yarrington
22 - Respiratory System, Pages 761-827, Wanda M. Haschek, Hanspeter R. Witschi
23 - Male Reproductive System, Pages 829-889, Dianne M. Creasy, Paul M.D. Foster
24 - Female Reproductive System, Pages 891-935, Yang-Dar Yuan
25 - Fetus, Pages 937-981, Colin G. Rousseaux, Patricia M. Blakley
26 - Radiation and Heat, Pages 983-1045, Stephen A. Benjamin, Barbara E. Powers, Kristen J. Nikula, Fletcher F. Hahn
Index, Pages 1047-1080