Handbook of Solid Phase Microextraction || Ligand—Receptor Binding and Determination of Free Concentrations
✍ Scribed by Musteata, Florin Marcel
- Book ID
- 121219897
- Publisher
- Elsevier
- Year
- 2012
- Tongue
- English
- Weight
- 499 KB
- Edition
- 2
- Category
- Article
- ISBN
- 0124160174
No coin nor oath required. For personal study only.
✦ Synopsis
The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This handbook offers a thorough background of the theory and practical implementation of SPME. SPME protocols are presented outlining each stage of the method and providing useful tips and potential pitfalls. In addition, devices and fiber coatings, automated SPME systems, SPME method development, and In Vivo applications are discussed.
This handbook is essential for its discussion of the latest SPME developments as well as its in depth information on the history, theory, and practical application of the method.
- Practical application of Solid Phase Microextraction methods including detailed steps
- Provides history of extraction methods to better understand the process
- Suitable for all levels, from beginning student to experienced practitioner
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The plasma protein binding of drugs has been shown to have significant effects on the quantitative relationship between clinical pharmacokinetics and pharmacodynamics. In many clinical situations, measurement of the total drug concentration does not provide the needed information concerning the unbo
The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic an