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[Handbook of Experimental Pharmacology] Analgesia Volume 177 || Protein Kinases as Potential Targets for the Treatment of Pathological Pain

โœ Scribed by Stein, Christoph


Book ID
111948799
Publisher
Springer Berlin Heidelberg
Year
2006
Tongue
German
Weight
494 KB
Edition
2007
Category
Article
ISBN
3540338225

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[Handbook of Experimental Pharmacology]
โœ Francis, Sharron H.; Conti, Marco; Houslay, Miles D. ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Springer Berlin Heidelberg ๐ŸŒ German โš– 201 KB

Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that