Handbook of Basal Ganglia Structure and Function

✍ Scribed by Heinz Steiner and Kuei Y. Tseng (Eds.)

• Publisher: Academic Press
• Year: 2010
• Leaves: 729
• Series: Handbook of Behavioral Neuroscience 20
• Edition: 1
• Category: Library

✦ Synopsis

The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson's disease, Tourette's syndrome, Huntington's disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction.

The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction.

*Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction *Features a truly international cast of the preeminent researchers in the field *Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases

✦ Table of Contents

Content:
Copyright
Page iv

Dedication
Page v

Contributors
Pages xix-xxii
Véronique M. André, Gordon W. Arbuthnott, Nigel S. Bamford, David Belin, Marianne Benoit-Marand, Hagai Bergman, Debra A. Bergstrom, Sandrine Betuing, Corinne Beurrier, Erwan Bezard, Javier Blesa, J. Paul Bolam, Karen Brami-Cherrier, Stephanie E. Bronson, Jocelyne Caboche, Paolo Calabresi, Anna R. Carta, M. Angela Cenci, Carlos Cepeda, Savio Chan, et al.

Preface
Pages xxiii-xxiv

Acknowledgements
Page xxv

Chapter 1 - The Neuroanatomical Organization of the Basal Ganglia
Pages 3-28
Charles R. Gerfen, J. Paul Bolam

Chapter 2 - The Conservative Evolution of the Vertebrate Basal Ganglia
Pages 29-62
Anton Reiner

Chapter 3 - Cell Types in the Different Nuclei of the Basal Ganglia
Pages 63-74
Dorothy E. Oorschot

Chapter 4 - Neurotransmitter Receptors in the Basal Ganglia
Pages 75-96
Piers C. Emson, Henry J. Waldvogel, Richard L.M. Faull

Chapter 5 - The Striatal Skeleton: Medium Spiny Projection Neurons and their Lateral Connections
Pages 99-112
Dietmar Plenz, Jeffery R. Wickens

Chapter 6 - D1 and D2 Dopamine Receptor Modulation of Glutamatergic Signaling in Striatal Medium Spiny Neurons
Pages 113-132
D. James Surmeier, Michelle Day, Tracy Gertler, Savio Chan, Weixing Shen

Chapter 7 - The Cholinergic Interneurons of the Striatum: Intrinsic Properties Underlie Multiple Discharge Patterns
Pages 133-149
Joshua A. Goldberg, Charles J. Wilson

Chapter 8 - GABAergic Interneurons of the Striatum
Pages 151-166
James M. Tepper

Chapter 9 - Endocannabinoid Signaling in the Striatum
Pages 167-186
David M. Lovinger, Margaret I. Davis, Rui M. Costa

Chapter 10 - Nitric Oxide Signaling in the Striatum
Pages 187-200
Anthony R. West

Chapter 11 - Role of Adenosine in the Basal Ganglia
Pages 201-217
Micaela Morelli, Nicola Simola, Patrizia Popoli, Anna R. Carta

Chapter 12 - Regulation of Corticostriatal Synaptic Plasticity in Physiological and Pathological Conditions
Pages 219-229
Massimiliano Di Filippo, Paolo Calabresi

Chapter 13 - Organization of the Globus Pallidus
Pages 233-247
Hitoshi Kita

Chapter 14 - Projections from Pallidum to Striatum
Pages 249-257
Pieter Voorn

Chapter 15 - The Subthalamic Nucleus: From In Vitro to In Vivo Mechanisms
Pages 259-273
Stephane Charpier, Corinne Beurrier, Jeanne T. Paz

Chapter 16 - Neurophysiology of Substantia Nigra Dopamine Neurons: Modulation by GABA
Pages 275-296
James M. Tepper

Chapter 17 - Regulation of Extracellular Dopamine: Release and Reuptake
Pages 297-319
David Sulzer, Hui Zhang, Marianne Benoit-Marand, Francois Gonon

Chapter 18 - Organization of Corticostriatal Projection Neuron Types
Pages 323-339
Anton Reiner

Chapter 19 - Gating of Cortical Input to the Striatum
Pages 341-351
Jeffery R. Wickens, Gordon W. Arbuthnott

Chapter 20 - Organization of Prefrontal-Striatal Connections
Pages 353-365
Henk J. Groenewegen, Harry B.M. Uylings

Chapter 21 - Gating of Limbic Input to the Ventral Striatum
Pages 367-379
Patricio O'Donnell

Chapter 22 - Anatomical and Functional Organization of the Thalamostriatal Systems
Pages 381-396
Yoland Smith, Adriana Galvan, Dinesh Raju, Thomas Wichmann

Chapter 23 - Subcortical Connections of the Basal Ganglia
Pages 397-408
Philip Winn, David I.G. Wilson, Peter Redgrave

Chapter 24 - Integrative Networks Across Basal Ganglia Circuits
Pages 409-427
Suzanne N. Haber

Chapter 25 - Synchronous Activity in Basal Ganglia Circuits
Pages 429-443
Judith R. Walters, Debra A. Bergstrom

Chapter 26 - Second-Messenger Cascades
Pages 447-460
Stephanie E. Bronson, Christine Konradi

Chapter 27 - Neurotransmitter Regulation of Basal Ganglia Gene Expression
Pages 461-490
Kristen A. Keefe, Kristen A. Horner

Chapter 28 - D1 Dopamine Receptor Supersensitivity in the Dopamine-Depleted Striatum: Aberrant ERK1/2 Signaling
Pages 491-500
Charles R. Gerfen

Chapter 29 - Psychostimulant-Induced Gene Regulation in Corticostriatal Circuits
Pages 501-525
Heinz Steiner

Chapter 30 - Chromatin Remodeling: Role in Neuropathologies of the Basal Ganglia
Pages 527-545
Jocelyne Caboche, Emmanuel Roze, Karen Brami-Cherrier, Sandrine Betuing

Chapter 31 - Phasic Dopamine Signaling and Basal Ganglia Function
Pages 549-559
Peter Redgrave, Veronique Coizet, John Reynolds

Chapter 32 - Role of Basal Ganglia in Habit Learning and Memory: Rats, Monkeys, and Humans
Pages 561-569
Mark G. Packard

Chapter 33 - Drug Addiction: the Neural and Psychological Basis of a Compulsive Incentive Habit
Pages 571-592
David Belin, Barry J. Everitt

Chapter 34 - Parkinson's Disease: Cross-Talk Between Environmental Factors and Gene Defects
Pages 593-606
Gloria E. Meredith, Susan Totterdell

Chapter 35 - Alterations in Corticostriatal Synaptic Function in Huntington's and Parkinson's Diseases
Pages 607-623
Carlos Cepeda, Nigel S. Bamford, Véronique M. André, Michael S. Levine

Chapter 36 - Molecular Mechanisms of l-DOPA-Induced Dyskinesia
Pages 625-640
M. Angela Cenci

Chapter 37 - Compensatory Mechanisms in Experimental and Human Parkinsonism: Potential for New Therapies
Pages 641-652
Erwan Bezard, Grégory Porras, Javier Blesa, José A. Obeso

Chapter 38 - Pathological Synchrony of Basal Ganglia-Cortical Networks in the Systemic MPTP Primate Model of Parkinson's Disease
Pages 653-658
Hagai Bergman, Adam Zaidel, Boris Rosin, Maya Slovik, Michal Rivlin-Etzion, Shay Moshel, Zvi Israel

Chapter 39 - Deep-Brain Stimulation for Neurologic and Psychiatric Disorders
Pages 659-681
Thomas Wichmann, Mahlon R. DeLong

Index
Pages 683-693