Haloperidol-induced disruption of conditioned avoidance responding: Attenuation by prior training or by anticholinergic drugs

Blockade of acquisition of one-way condi

Blockade of acquisition of one-way conditioned avoidance responding by haloperidol and metoclopramide but not by thioridazine or clozapine: implications for screening new antipsychotic drugs

✍ James R. Blackburn; Anthony G. Phillips 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 803 KB

The classical neuroleptic drugs haloperidol and pimozide have a strong disruptive effect on the acquisition of conditioned avoidance responding (CAR), yet have relatively little impact on the performance of previously acquired responses. Separate experiments compared the effects of haloperidol, two