𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Halogenated analogues of tamoxifen: Synthesis, receptor assay, and inhibition of MCF7 cells

✍ Scribed by David J. Yang; Timothy Tewson; Wayne Tansey; Li-Ren Kuang; Gregg Reger; Abdallah Cherif; Kenneth C. Wright; R. Gene Moult; Roy S. Tilbury; Kevin Chu; E. Edmund Kim; Sidney Wallace

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
425 KB
Volume
81
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Effect of tamoxifen and retinoic acid on
Effect of tamoxifen and retinoic acid on bradykinin induced proliferation in MCF-7 cells
✍ Paola Searovic; Marcelo Alonso; Carolina Oses; Karla Pereira-Flores; Victoria Ve πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 247 KB πŸ‘ 1 views

## Abstract Chemopreventive approaches for the treatment of breast cancer have been validated clinically and with in vitro studies. The combined action of tamoxifen/all‐trans retinoic acid was advantageous in MCF‐7 cells, reducing cell proliferation, Bcl‐2 and c‐Myc protein levels and increasing E‐

Additive effects of tamoxifen and the fa
Additive effects of tamoxifen and the farnesyl transferase inhibitor FTI-277 on inhibition of MCF-7 breast cancer cell-cycle progression
✍ Sophie F. Doisneau-Sixou; Philippe Cestac; Jean-Charles Faye; Gilles Favre; Robe πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 394 KB πŸ‘ 1 views

## Abstract The efficacy of tamoxifen in the hormonal therapy of breast cancer is well established, but therapeutic resistance is inevitable. FTIs are a new class of anticancer drugs that are in phase III clinical evaluation. Since the mechanisms of action of these 2 classes of drugs are different,

RNAi-mediated silencing of insulin recep
RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells
✍ Gregory Cesarone; Cecilia Garofalo; Marc T. Abrams; Olga Igoucheva; Vitali Alexe πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 269 KB

## Abstract Insulin receptor substrate 1 (IRS‐1) is a major downstream signaling protein for insulin and insulin‐like growth factor I (IGF‐I) receptors, conveying signals to PI‐3K/Akt and ERK1/2 pathways. In breast cancer, IRS‐1 overexpression has been associated with tumor development, hormone‐ind