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Halogen bonding for rational drug design and new drug discovery

✍ Scribed by Lu, Yunxiang; Liu, Yingtao; Xu, Zhijian; Li, Haiying; Liu, Honglai; Zhu, Weiliang

Book ID
111861194
Publisher
Informa plc
Year
2012
Tongue
English
Weight
436 KB
Volume
7
Category
Article
ISSN
1746-0441

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## Abstract A halogen bond is a noncovalent bond between a halogen atom (X) and a Lewis base (Y). This type of bond is attributed to the anisotropic distribution of the charge density on the halogen atom, resulting in the formation of a positive cap (called the σ‐hole) centered on the A–X axis. The