Halide interacti witonh phospholipids: Proton magnetic resonance studies

✍ Scribed by Gordon L. Jendrasiak

• Publisher: Elsevier Science
• Year: 1972
• Tongue: English
• Weight: 605 KB
• Volume: 9
• Category: Article
• ISSN: 0009-3084
• DOI: 10.1016/0009-3084(72)90009-6

✦ Synopsis

Water dispersions of egg phosphatidyl choline, dioleoyl phosphatidyl choline and lyso egg phosphatidyl choline have been studied by means of 220 MHz proton magnetic resonance techniques. The N+(CHa)a proton signal, for phosphatidyl choline vesicles, consists of two components. The two components are thought to arise from N+(CHa)a groups interior and exterior to the phosphatidyl choline vesicle. Anions were found to increase the separation of the two components. The effectiveness of the anions follows their order in the lyotropic series. For a given anion, the increase in component separation depends on the nature of the phospholipid. Iodine was found to modify the anion effect. The results are related to the results of other workers on water transport across lipid bilayer membranes and on phospholipid-halide-binding.