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Half-life and Renal Excretion of Trimethoprim in Swine

โœ Scribed by Nielsen, Poul ;Rasmussen, Folke

Book ID
114799068
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
362 KB
Volume
36
Category
Article
ISSN
0001-6683

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Renal excretion of emtricitabine II. Eff
Renal excretion of emtricitabine II. Effect of trimethoprim on emtricitabine excretion: In vitro and in vivo studies
โœ Tomoko Nakatani-Freshwater; David R. Taft ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 138 KB

The potential interaction between the nucleoside analog emtricitabine (FTC) and trimethoprim (TMP) was assessed in the isolated perfused rat kidney (IPK) model and in vivo in rats. IPK experiments were performed with FTC alone (2 mg/mL) and in the presence of increasing concentrations of TMP (1-10 m