A membrane antigen with an apparent specificity to B lymphocytes was detected with immunochemical techniques and its properties were analyzed. Anti-B-CLL serum was raised in a rabbit by immunization with B-cell chronic lymphocytic leukemia (B-CLL) cells. This anti-B-CLL serum was absorbed with eryth
Hairy cell leukemia: A B-lymphocytic disorder derived from splenic marginal zone lymphocytes?
โ Scribed by Oord, J. J. ;Wolf-Peeters, C. ;Desmet, V. J.
- Publisher
- Springer-Verlag
- Year
- 1985
- Weight
- 300 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1432-0584
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It has been suggested that lymphocytes of mucosa-associated lymphoid tissue (MALT) arise from marginal zone cells and that MALT-derived lymphomas may spread to other extra-nodal sites by homing to marginal zones in different tissues.' Marginal zone expansion has been observed in spleens removed duri