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Hairpin DNA probe based electrochemical biosensor using methylene blue as hybridization indicator

✍ Scribed by Yan Jin; Xin Yao; Qing Liu; Jinghong Li

Book ID: 108071764
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 327 KB
Volume: 22
Category: Article
ISSN: 0956-5663
DOI: 10.1016/j.bios.2006.04.011

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## Abstract Electrochemical detection of nucleic acid base mismatches related to Apa I single nucleotide polymorphism (SNP) in the vitamin D receptor gene was performed successfully using 7‐dimethyl‐amino‐1,2‐benzophenoxazinium salt (Meldola's blue, MDB) with 10.9 pmol/100 μL of detection limit. MD