Hair follicle stem cell-targeted gene transfer and reconstitution system

Stem cell antigen-1 positive cell-based

Stem cell antigen-1 positive cell-based systemic human growth hormone gene transfer strategy increases endosteal bone resorption and bone loss in mice

✍ Susan L. Hall; Shin-Tai Chen; Jon E. Wergedal; Daila S. Gridley; Subburaman Moha 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 358 KB

## Abstract ## Background The present study assesses the effect of the stem cell antigen‐1 positive (Sca‐1^+^) cell‐based human growth hormone (hGH) __ex vivo__ gene transfer strategy on endosteal bone mass in the mouse. ## Methods Sublethally irradiated recipient mice were transplanted with Sca