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Haemostatic alterations in colorectal cancer: Perspectives for future treatment

✍ Scribed by Jakob Lykke; Hans Jørgen Nielsen

Book ID
102437027
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
85 KB
Volume
88
Category
Article
ISSN
0022-4790

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✦ Synopsis

Abstract

The role of the haemostatic system in colorectal cancer (CRC) is reviewed. Correlations between the activation of the haemostatic system and overall survival have been suggested. Experimental studies indicate that the haemostatic system plays a key role in growth, invasion and dissemination of tumour cells, and in tumour related angiogenesis. Additional activation by the surgical trauma and postoperative infections are discussed. Finally, anti‐cancer modalities directed against regulation of the haemostatic system in CRC are considered. J. Surg. Oncol. 2004;88:269–275. © 2004 Wiley‐Liss, Inc.

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