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Haemolytic Activity and Immunological Adjuvant Effect of a New Steroidal Saponin from Allium ampeloprasum var. porrum

✍ Scribed by Camila Rodrigues Adão; Bernadete Pereira da Silva; Luzineide Wanderley Tinoco; José Paz Parente

Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 338 KB
Volume: 9
Category: Article
ISSN: 1612-1872
DOI: 10.1002/cbdv.201100005

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✦ Synopsis

A new steroidal saponin was isolated from the bulbs of Allium ampeloprasum L. var. porrum. On the basis of chemical evidence, comprehensive spectroscopic analyses, and comparison with known compounds, its structure was established as (3b,5a,6b,25R

. Results of the present study indicated that 1 exhibited haemolytic activity in the in vitro assays, and immunological adjuvant activity on the cellular immune response against ovalbumin antigen.

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