Haematology and serum biochemistry in the racing greyhound following intraperitoneal povidone-iodine
✍ Scribed by J. Ndikuwera; E. W. Winstanley; G. Binta-Mushi; E. Z. Mushi
- Publisher
- Springer Netherlands
- Year
- 1988
- Tongue
- English
- Weight
- 610 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0165-7380
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✦ Synopsis
Haematology and serum biochemistry in the racing greyhound following intraperitoneal povidone-iodine. Veterinary Research Communications, 12 (l), 77-86.
Povidone-iodine caused peritonitis with neutrophilic leukocytosis and a minimal left shift at the dosage rate of 3.5 ml/kg body weight. A dosage rate of 2 ml/kg only caused slight neutrophilic leukocytosis. There was a significant increase in the levels of creatinine (p = 0.049) and BUN (p = 0.020) in dogs that received the higher dose rate. Two dogs died from povidone-iodine toxicity with a marked increase in ALT, AP, SDH and conjugated bilirubin. It is concluded that povidone-iodine is unsafe for use in the peritoneal cavity of dogs.