## Yp -specific sequences, including the testicular determinant gene SRY, have been detected and located in a 46,XX true hermaphrodite individual, using PCR amplification and fluorescent in situ hybridization (FISH). Among different Y chromosome loci tested, it was only possible to detect Yp sequen
H-Y gene expression in apparent absence of the long arm of the Y chromosome
β Scribed by Moreira-Filho, Carlos Alberto ;Otto, Priscilla G. ;Frota-Pessoa, Oswaldo ;Summitt, Rovert L.
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 263 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0148-7299
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β¦ Synopsis
H-Y antigen expression was detected on cells from an individual having a presumptive 45,X/46,X,i(Yp) karyotype, but was absent on cells from another person having a 46,X,i(Yq) karyotype. This suggests that the short arm of the human Y chromosome is essential for H-Y antigen expression, at least in the subjects studied.
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