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H-ras oncogene point mutations in arthritic synovium

✍ Scribed by Anne Roivainen; Jari Jalava; Laura Pirilä; Tuomas Yli-Jama; Hannu Tiusanen; Paavo Toivanen


Book ID
102750993
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
868 KB
Volume
40
Category
Article
ISSN
0004-3591

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Bladder tumors respond to cisplatin-based chemotherapy in 68% of cases, but only 30% will have a durable response. Recent studies have suggested that ras point mutations may produce cisplatin drug resistance in cell lines. To determine the role of ras point mutations in human tumors resistant to cis