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H-ras Mutation Detection in Bladder Cancer by COLD-PCR Analysis and Direct Sequencing

โœ Scribed by Wang, Ai-Xiang; Chang, Ji-Wu; Li, Chang-Ying; Liu, Kun; Lin, Ying-Li


Book ID
120180055
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
337 KB
Volume
88
Category
Article
ISSN
0042-1138

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Detection of a rare point mutation in Ki
โœ Grimmond, S. M. ;Raghavan, D. ;Russell, P. J. ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 615 KB

This paper represents the first report of a codon 59 mutation in Ki-ras from a spontaneous human transitional cell carcinoma of the bladder. Point mutations have the potential to activate the ras genes if they occur in critical coding regions. These include the sequences of codons 12, 13, 59, 61 and