Gβγ subunits stimulate p21-activated kinase 1 (PAK1) through activation of PI3-kinase and Akt but act independently of Rac1/Cdc42

Stimulation by ghrelin of p42/p44 mitoge

Stimulation by ghrelin of p42/p44 mitogen-activated protein kinase through the GHS-R1a receptor: Role of G-proteins and β-arrestins

✍ Jesus P. Camiña; Maria Lodeiro; Olga Ischenko; Ana C. Martini; Felipe F. Casanue 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 582 KB

## Abstract Results presented in this study indicate that in human embryonic kidney 293 cells (HEK 293), the ghrelin receptor growth hormone secretagogue receptor type 1a (GHS‐R1a) activates the extracellular signal‐related kinases 1 and 2 (ERK 1/2) via three pathways. One pathway is mediated by th