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Gypenosides protects dopaminergic neurons in primary culture against MPP+-induced oxidative injury

โœ Scribed by Peng Wang; Le Niu; Xiao-Dong Guo; Li Gao; Wei-Xin Li; Dong Jia; Xue-Lian Wang; Lian-Ting Ma; Guo-Dong Gao

Book ID
116327123
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
695 KB
Volume
83
Category
Article
ISSN
0361-9230

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Parkinson's disease is characterized by chronic progression of dopaminergic neuronal death, the mechanism of which is still unknown. Although methyl-4-phenylpyridium ion (MPP+) or MPP+-like substance, that can reduce mitochondrial complex I activity, is supposed to be a causative agent for Parkinson