Gynecologic Radiation Oncology: A Practical Guide

✍ Scribed by Patricia Eifel, Ann H. Klopp

• Publisher: LWW
• Year: 2016
• Tongue: English
• Leaves: 621
• Edition: 1
• Category: Library

✦ Synopsis

Offering practical approaches to common clinical problems, Gynecologic Radiation Oncology: A Practical Guide compiles the extensive clinical experience of Drs. Patricia J. Eifel and Ann H. Klopp from MD Anderson Cancer Center into one user-friendly volume. This reference addresses practical aspects of the field: how to evaluate the role of radiation therapy in various clinical settings, how to explain the rationale for treatment recommendations to referring physicians and patients, when and how to apply various external beam and brachytherapy techniques to address specific clinical problems, and how to monitor and manage patients during and after treatment. The book focuses on the following items, which can have immediate application to the treatment of patients with gynecologic cancers.
Key Features:

• Addresses the techniques, methods, and challenging decisions that characterize the day-to-day practice of gynecologic radiation oncology.
• Features more than 700 figures and tables that highlight key information – from initial patient evaluation and treatment recommendation, through the process of radiation treatment planning and delivery, to post-treatment monitoring of patients for recurrence and treatment-related side effects.
• Covers sites of origin, the principles of tumor biology, multidisciplinary management, clinical evaluation, radiation therapy treatment planning and delivery, and symptom management, as well as the features of individual disease sites.
• Includes more than 50 case studies that demonstrate how concepts are applied in real-life clinical situations.
• Provides references that are particularly helpful in clinical decision-making, emphasizing important clinical trials, meta-analyses of relevant data and high-quality review articles.
• Explains not only the insights gained from the clinical literature but also the opportunities for misinterpretation, suggesting how trial results can be more accurately applied to everyday clinical practice.
• Uses extensive cross-referencing throughout to help you navigate the text and find related topics quickly.

Purchase of the print addition includes a bundled interactive eBook, which can be downloaded to your tablet and smartphone or accessed online and includes features such as:

• Complete content with enhanced navigation

Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web

• Cross-linked pages, references, and more for easy navigation
• Highlighting tool for easier reference of key content throughout the text
• Ability to take and share notes with friends and colleagues
• Quick reference tabbing to save your favorite content for future use

✦ Table of Contents

Cover
Title
Copyright
Dedication
Preface
Acknowledgments
Contents
Part I • PRINCIPLES OF GYNECOLOGIC ONCOLOGY
1 Pathology, Molecular Biology, and Etiology of Gynecologic Cancers
Correlates between Morphology and Biologic Behavior
Molecular Biology of Gynecologic Cancers
Role of HPV in Gynecologic Cancers
Hereditary Cancer Syndromes
2 Interpretation of Clinical Research Results as They Apply to Daily Practice
Ambiguities Caused by Inconsistent Nomenclature
Evaluating the Nature and Validity of Trial End Points
Observational Studies
The Benefits and Limitations of Randomized Trials
Meta-analysis
Big Data: Outcomes Analysis
3 Principles of Multidisciplinary Management
The Multidisciplinary Team
Choosing and Sequencing Locoregional Treatments
Efficacy and Sequencing of Combined Chemotherapy and RT
Part II • PRINCIPLES OF RADIATION THERAPY PLANNING AND DELIVERY
4 Preparation for Radiation Treatment Planning
Information Gathering—The Initial Patient Evaluation
Development of an Overall Radiation Treatment Strategy
Patient Set-Up and Simulation for External Beam Radiation Therapy
5 Applied Anatomy and Target Volume Definition
Target Volume Definition
Regional Lymph Nodes
Reproductive Organs
Target Volume Definition: Final Review
6 External Beam Radiation Treatment Planning
The Treatment Planning Directive
Accounting for Uncertainties—Designation of the PTV
Normal Tissue Constraints for External Beam Planning
External Beam Radiation Technique
Treatment Plan Evaluation, Documentation, and Quality Assurance
7 Monitoring During Treatment
Social Circumstances, Nutrition, and Coexisting Medical Conditions100
Monitoring Progress toward Completion of the Treatment Plan
Evaluation and Management of Acute Treatment-Related Adverse Effects
Monitoring the Accuracy of Daily Treatment
8 Brachytherapy
Essential Elements of a Brachytherapy Treatment Plan114
Gynecologic Brachytherapy Applicators
Applicator Placement
Brachytherapy Treatment Planning
9 Posttreatment Monitoring
The Survivorship Care Plan
Monitoring for Cancer Recurrence
Monitoring and Management of Late Adverse Effects of Treatment
Risk of and Surveillance for Second Malignancies
Part III • SITE-SPECIFIC INDICATIONS AND TECHNIQUES
10 Cervical Cancer
Pretreatment Evaluation and Staging
Risk Assessment
Multidisciplinary Treatment
RT for Intact Cervical Cancer161
Treatment of Recurrent Disease
Case Studies
11 Vaginal Cancer
Pretreatment Evaluation and Staging
Risk Assessment
Multidisciplinary Considerations
Developing a Radiation Treatment Strategy
Management Considerations According to Tumor Location
Case Studies
12 Vulvar Cancer
Pretreatment Evaluation
Risk Assessment
Developing a Multidisciplinary Treatment Strategy
Technical Considerations
Case Studies
13 Uterine Cancer
Pretreatment Evaluation
Risk Assessment
Developing a Multidisciplinary Treatment Strategy
Management Considerations According to Disease Extent
Case Studies
14 Ovarian Cancer
Presentation and Patterns of Spread
Prognostic Factors
Roles of Surgery and Chemotherapy
Role of RT
Developing a Radiation Treatment Strategy
RT for Nonepithelial Ovarian Cancers
Case Studies
15 Unknown Primary
Pretreatment Evaluation
Risk Assessment
Multidisciplinary Treatment Strategy
Radiation Therapy—Technical Considerations
Case Studies
16 Palliation
Indications for Palliative Radiation Therapy
Conditions for Which Palliative Radiation Therapy Is Generally Not Indicated
Index