## Abstract ## BACKGROUND. Women with Lynch syndrome (hereditary nonpolyposis colorectal cancer) have an increased lifetime risk for endometrial and ovarian cancer. Screening and prophylactic surgery have been recommended as prevention strategies. In this study, the authors estimated the net healt
Gynecologic cancers associated with Lynch syndrome/HNPCC
β Scribed by Kathleen M. Schmeler; Karen H. Lu
- Publisher
- Springer Milan
- Year
- 2008
- Tongue
- Spanish
- Weight
- 93 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1699-048X
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π SIMILAR VOLUMES
## Communicated by Mauno Vihinen Mutations in some mismatch repair (MMR) genes are associated with Lynch syndrome (LS; also called hereditary nonpolyposis colorectal cancer [HNPCC]), an autosomal dominant cancer susceptibility syndrome. Colorectal cancer (CRC) is the most frequent cancer observed
DNA flow cytometry was performed on 44 paraffin blocks from 16 specimens of 11 lesions in five patients from two families identified as probably having the dominant gene of the Lynch Type I1 syndrome. All but one specimen showed diploidy, although two such specimens were metastases and one a recurre