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Gymnocin-A, a Cytotoxic Polyether from the Notorious Red Tide Dinoflagellate, Gymnodinium mikimotoi.

✍ Scribed by Masayuki Satake; Mitsuha Shoji; Yasukatsu Oshima; Hideo Naoki; Tsuyoshi Fujita; Takeshi Yasumoto

Book ID
101933090
Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
33
Category
Article
ISSN
0931-7597

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Gymnocin-A, a cytotoxic polyether from t
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A new cytotoxic polyether, gymnocin-A, was isolated from the notorious red tide dinoflagellate, Gymnodinium mikimotoi, and its structure consisting of 14 contiguous ether rings and a 2-methyl-2-butenal side-chain was determined by NMR and CID MS/MS experiments.

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## Abstract __Heterocapsa circularisquama__ is known to cause lethal effect on bivalves, but toxic effect on fish has not been reported yet. Recently, we have found that __H. circularisquama__ has potent light‐dependent hemolytic toxins. Based on the chemical structural analysis, one of the hemolyt