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Guillain-Barré syndrome triggered by influenza vaccination in a recipient of liver transplant on FK506

✍ Scribed by Joon-Shik Moon; Nizar Souayah


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
67 KB
Volume
12
Category
Article
ISSN
1527-6465

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✦ Synopsis


Guillain-Barre ´syndrome (GBS) has been rarely reported after liver transplantation and generally has good outcome. We report a liver transplant patient on FK506 (tacrolimus) who developed GBS 6 months after liver transplantation. There was no evidence of liver rejection or active infection. Despite treatment with intravenous immunoglobulin, the patient expired. GBS occurred despite downregulation of T cells by FK506, suggesting that humoral dysfunction might be the predominant mechanism of GBS in this report.