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Guillain-Barré syndrome after varicella-zoster infection

✍ Scribed by E. A. C. M. Sanders; A. C. B. Peters; J. W. Gratana; R. A. C. Hughes

Publisher
Springer
Year
1987
Tongue
English
Weight
311 KB
Volume
234
Category
Article
ISSN
0340-5354

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✦ Synopsis

Two patients developed Guillain-Barré syndrome after varicella-zoster infection; a 4-year-old boy after chickenpox and a 74-year-old man after shingles. Both had decreased CD8-positive lymphocytes in the blood during the course of their illness. These cases and others reported in the literature suggest that varicella-zoster infection is a significant but rare trigger factor of Guillain-Barré syndrome. An alteration in the balance of helper and suppressor lymphocytes may be an important pathogenetic mechanism.

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