Guidelines for the diagnosis of fragile X
β Scribed by Miguel A. De Arce; Frederick Hecht; Grant R. Sutherland; Graham C. Webb
- Book ID
- 115089471
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 68 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0009-9163
No coin nor oath required. For personal study only.
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We reviewed the distribution of autosomal fragile sites (FS) and spontaneous chromosome breaks or gaps (CB) at chromosome locations other than those recognized as FS from 100 amniotic fluid samples (AF), 19 chorionic villus samples (CVS), and 5 percutaneous umbilical blood samples (PUBS) referred fo
Several organizations have proposed guidelines for fra(X) studies on peripheral blood lymphocytes. To evaluate these guidelines, we reviewed 1,033 consecutive specimens referred for fra(X) analysis. Each specimen was cultured with medium 199 and RPMI 1640 with 5-fluorodeoxyuridine or excess thymidin